Indian Journal of Medical Microbiology IAMM  | About us |  Subscription |  e-Alerts  | Feedback |  Login   
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size
 Home | Ahead of Print | Current Issue | Archives | Search | Instructions  
Users Online: 1523 Official Publication of Indian Association of Medical Microbiologists 
 ~ Next article
 ~ Previous article 
 ~ Table of Contents
 ~  Similar in PUBMED
 ~  Search Pubmed for
 ~  Search in Google Scholar for
 ~  Article in PDF (76 KB)
 ~  Citation Manager
 ~  Access Statistics
 ~  Reader Comments
 ~  Email Alert *
 ~  Add to My List *
* Registration required (free)  

 ~  References
 ~  Article Tables

 Article Access Statistics
    PDF Downloaded490    
    Comments [Add]    
    Cited by others 3    

Recommend this journal


Year : 2008  |  Volume : 26  |  Issue : 2  |  Page : 206-207

Leptospirosis laboratory, Madras medical college: Review of our experience (2004-2006)

1 Institute of Microbiology, Madras Medical College, Chennai - 600 003, India
2 Leptospirosis Laboratory, Madras Medical College, Chennai - 600 003, India
3 Department of Medicine, Stanley Medical College and Hospital, Chennai - 600 001, India

Date of Submission25-Jul-2007
Date of Acceptance26-Jul-2007

Correspondence Address:
G Sumathi
Institute of Microbiology, Madras Medical College, Chennai - 600 003
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0255-0857.40553

Rights and Permissions

How to cite this article:
Sumathi G, Narayanan R, Shivakumar S. Leptospirosis laboratory, Madras medical college: Review of our experience (2004-2006). Indian J Med Microbiol 2008;26:206-7

How to cite this URL:
Sumathi G, Narayanan R, Shivakumar S. Leptospirosis laboratory, Madras medical college: Review of our experience (2004-2006). Indian J Med Microbiol [serial online] 2008 [cited 2020 May 25];26:206-7. Available from:

Dear editor,

The Leptospira laboratory in Madras Medical College at Chennai was established in 1994. We have already published our experience during the period 1995-1997. [1] In this article, we discuss our experience during the period 2004-2006, with the samples received from public hospitals in Chennai. There has been a dramatic increase in the numbers of both samples and of positive cases, probably because of increased awareness of the illness [Table - 1]. These samples were from patients suffering from fever. During 2006, 2765 positive cases were reported from public sector hospitals. The data of numbers of samples and positive samples from city hospitals are shown in [Table - 2]. Government Stanley Hospital (GSH) caters to patients from North Chennai while Government Royapettah Hospital (GRH) caters to patients from south Chennai. Government General Hospital (GGH) and Kilpauk Medical College and Hospital (KMC) cater to patients from central Chennai and the surrounding areas. The Institute of Child Health (ICH) caters to children from all areas.

Samples were received throughout the year and the data reveal that leptospirosis occurs throughout the year although the number may increase during the monsoon season (June to January). This emphasizes the importance of a polluted environment which is an important epidemiological risk factor.

It has been our policy to do the macroscopic slide agglutination test (MSAT) as a screening test for all the samples received. All positive MSAT results are confirmed by the Microscopic Agglutination Test (MAT). [2],[3],[4] Nine pathogenic and one nonpathogenic serovars were included in antigen preparation. L.icterohaemorrhagiae, L. australis, L. grippotyphosa, L. pomona, L. sejroe, L. bataviae, L. louisiana, L. hebdomadis, L. javanica and L. patoc were the serovars used. The antigen was prepared using standard methods. [5]

The common serovars found were L. icterohaemorrhagiae (48.0%) followed by L. australis (37.0%) and L. grippotyphosa (26.0%). During our study in 1995-1997, L. autumnalis (48.3%) was found to be the predominant serovar followed by L. icterohaemorrhagiae (31.1%). [1]

Therefore, we conclude that there has been a dramatic increase in the number of leptospirosis cases reported in our laboratory during the period 2004-2006 and the common serovars are L. icterohaemorrhagiae, L. australis and L. grippotyphosa. We also conclude that leptospirosis in Chennai occurs throughout the year.

 ~ References Top

1.Pradeep KS, Sumathi G, Rao GV, Kumar SS. Leptospirosis laboratory, Chennai Medical College: A three year experience in serodiagnosis (1995-1997). Indian J Med Microbiol 1999;17:50-1.  Back to cited text no. 1    
2.Shivakumar S, Krishnakumar B. Diagnosis of leptospirosis: Role of mat. J Assoc Physicians India 2006;54:338-9.  Back to cited text no. 2  [PUBMED]  
3.Sumathi G, Pradeep KS, Subudhi CH, Helen PS, Kalpana, Shivakumar S, et al. Serodiagnosis of leptospirosis: A Madras study. Indian J Med Microbiol 1995;13:192-5.  Back to cited text no. 3    
4.Sumathi G, Shivakumar S, Chinari Pradeep KS. MSAT: A screening test for leptospirosis. Indian J Med Microbiol 1997;15:84.  Back to cited text no. 4    
5.Faine S, editor. WHO Guidelines for the control of leptospirosis. Geneva; WHO Offset publication No.67; 1982.  Back to cited text no. 5    


  [Table - 1], [Table - 2]

This article has been cited by
1 Does leptospirosis behave adversely in cirrhosis of the liver?
Aravindh Somasundaram,Nattusamy Loganathan,Joy Varghese,Singh Shivakumar,Venkataraman Jayanthi
Indian Journal of Gastroenterology. 2014;
[Pubmed] | [DOI]
2 Occurrence of leptospirosis among suspected cases in Chennai, Tamil Nadu
Arumugam, G., Mini Jacob, S., Anitha, D., Rajappa, S.M.
Indian Journal of Pathology and Microbiology. 2011; 54(1): 100-102
3 Increasing trends of leptospirosis in Northern India: A clinico-epidemiological study
Sethi, S., Sharma, N., Kakkar, N., Taneja, J., Chatterjee, S.S., Banga, S.S., Sharma, M.
PLoS Neglected Tropical Diseases. 2010; 4(1)


Print this article  Email this article
Previous article Next article


2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04