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CORRESPONDENCE
Year : 2006  |  Volume : 24  |  Issue : 1  |  Page : 78-79
 

How reliable are serological tests in diagnosis of cysticercosis?


Department of Microbiology, Maulana Azad Medical College and LN Hospital, New Delhi - 110 003, India

Correspondence Address:
V Wadhwa
Department of Microbiology, Maulana Azad Medical College and LN Hospital, New Delhi - 110 003
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0255-0857.19908

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How to cite this article:
Wadhwa V, Kharbanda P, Rai S. How reliable are serological tests in diagnosis of cysticercosis?. Indian J Med Microbiol 2006;24:78-9

How to cite this URL:
Wadhwa V, Kharbanda P, Rai S. How reliable are serological tests in diagnosis of cysticercosis?. Indian J Med Microbiol [serial online] 2006 [cited 2019 Sep 18];24:78-9. Available from: http://www.ijmm.org/text.asp?2006/24/1/78/19908


Dear Editor,

Human cysticercosis occurs when man becomes the intermediate host by being infested with eggs of Taenia solium. Diagnosis is based on combination of direct visualization, histology, serology and imaging techniques. Use of single diagnostic modality has low sensitivity.[1] Diagnosis of cysticercosis is important due to a probable involvement of the central nervous system.[2]

We describe a case of ocular (subconjunctival) cysticercosis in a eighteen years old, vegetarian male, who presented to the ophthalmology OPD with complaints of increasing painless conjunctival swelling of left eye since four months associated with redness, restriction of gaze and diplopia. The patient had a history of similar swelling in tongue three months back, which extruded spontaneously. The cystic swelling was excised in toto and the conjunctival defect was sutured. The patient was prescribed albendazole (15mg./kg) for three weeks. The cyst was 7mm x 5mm, white, translucent (live) and had a dense white spot which showed presence of a single scolex [Figure - 1].

The serology for T. solium ( T. solium IgG IVD Research Inc. Carlsbad, CA 92008) was negative. The serum immunoglobulin levels were within normal range. Stool samples, examined twice, did not show evidence of T. solium infestation. Computed tomography could not be done due to economic constraints.

The report demonstrates the poor sensitivity of immunological studies to detect cases of histologically proven cysticercosis, thus questioning their use in screening patients of suspected cysticercosis.

 
 ~ References Top

1.Garcia VH, Gonzalez AE, Evans CA, Gilman RH. Taenia solium cysticercosis. Lancet 2003; 362 :547-56.  Back to cited text no. 1    
2.Chowdhary A, Bansal R, Singh K, Singh V. Ocular cysticercosis- a profile. Trop Doc 2003; 33 :185-8.  Back to cited text no. 2  [PUBMED]  [FULLTEXT]


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1 Viscoexpression of large free floating cysticercus cyst from the anterior chamber of the eye by double incision technique
Kai, S., Vanathi, M., Vengayil, S., Panda, A.
Indian Journal of Medical Microbiology. 2008; 26(3): 277-279
[Pubmed]



 

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