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Year : 2004  |  Volume : 22  |  Issue : 2  |  Page : 107-111

Sensitivity index of antimicrobial agents: A new treatment criteria proposed for rational use of antimicrobials


1 National Institute of Biologicals, Min. Health and Family Welfare, A-32, Sector-62, Institutional Area, Noida - 201307, Uttar Pradesh, India
2 World Health House, WHO Regional Office for South East Asia, Indraprastha Estate, Ring Road, New Delhi - 110 002, India

Correspondence Address:
P Achla
National Institute of Biologicals, Min. Health and Family Welfare, A-32, Sector-62, Institutional Area, Noida - 201307, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


PMID: 17642706

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The treatment guidelines are generally decided on the basis of either percent resistant (%R) or percent sensitive (%S) bacterial population tested with a given antimicrobial that vary geographically and represent only a part of total bacterial population existing in response to the antimicrobial used. The isolates with intermediate sensitivity (%I) are either not reported or clubbed with resistant isolates though the two may differ in clinical response. Sensitivity Index (SI) of an antimicrobial is sensitive to change in any of the three co-existing bacterial population and may be a better criterion for rational use of antimicrobial.






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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04