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Year : 2004  |  Volume : 22  |  Issue : 1  |  Page : 54-56

Intestinal parasitic infection and total serum IgG in asymptomatic adult males in an urban slum and efficacy of antiparasitic therapy


1 Department of Microbiology, St. John's Medical College, Bangalore - 560 034, Karnataka, India
2 Department of Physiology, St. John's Medical College, Bangalore - 560 034, Karnataka, India

Correspondence Address:
S Nagaraj
Department of Microbiology, St. John's Medical College, Bangalore - 560 034, Karnataka
India
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PMID: 17642688

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Malnutrition is thought to potentiate the polyclonal stimulation of IgE by parasites. This diminishes immunity due to the decrease in specific anti-parasitic IgE. Prevalence of intestinal parasitic infections in chronically undernourished, asymptomatic adult males from a slum and efficacy of anti-parasitic therapy and its effect on total serum IgE were evaluated. Stool specimens from 51 subjects were examined. Anti-helminth and anti-protozoan therapy consisted of oral, single dose albendazole (400mg) and tinidazole (2g) respectively. Total serum IgE was measured. 23 (45.1%) subjects were positive. Albendazole and tinidazole cleared intestinal parasites but had no significant effect on total serum IgE levels.






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2004 - Indian Journal of Medical Microbiology
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