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Year : 2003  |  Volume : 21  |  Issue : 3  |  Page : 196-198

Emergence of low level vancomycin resistance in MRSA


Department of Clinical Microbiology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir - 190 011, India

Correspondence Address:
D K Kakru
Department of Clinical Microbiology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir - 190 011
India
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Source of Support: None, Conflict of Interest: None


PMID: 17643019

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One hundred and twenty methicillin resistant Staphylococcus aureus (MRSA) strains were checked for minimum inhibitory concenteration (MIC) of vancomycin. The results showed that 98 strains (81.7 %) had MIC < 4g/mL, 18 strains (15 %) had MIC 8 g/mL, and 4 (03.3%) had MIC 16 g/mL which being borderline between sensitive (< 4g/mL) and resistant (>32g/mL) values points towards possible emergence of low level vancomycin resistance in the organisms and may explain the reasons of delayed therapeutic success of vancomycin in S.aureus bacteraemia in some situations.






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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04