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 ORIGINAL ARTICLE
Year : 2001  |  Volume : 19  |  Issue : 2  |  Page : 52-56

Prevalence of specific IGM due to toxoplasma, rubella, CMV and c.trachomatis infections during pregnancy


National Institute of Nutrition, Indian council of Medical Research, Jamai Osmania P.O., Hyderabad, - 500 007, India

Correspondence Address:
P Yasodhara
National Institute of Nutrition, Indian council of Medical Research, Jamai Osmania P.O., Hyderabad, - 500 007
India
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Source of Support: None, Conflict of Interest: None


PMID: 17664809

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One hundred and seventy five apparently normal asymptomatic pregnant women were studied prospectively and 247 women with different complications of pregnancy were screened at the time of delivery for infections like Chlamydia trachomatis, Toxoplasma, Rubella and cytomegalovirus (CMV). One hundred and forty two women with normal outcome of pregnancy served as controls. Specific IgM due to these agents were determined in the sera using commercial diagnostic kits. Results of the study showed that chlamydial infection was the most prevalent (29.8%) followed by Toxoplasmosis (13.1), Rubella (6.5%) and CMV (5.8%). Adverse outcome was seen among those seropositive for Chlamydia, Toxoplasmosis and Rubella. CMV showed no association with adverse outcome of pregnancy. Since Chlamydia and Toxoplasmosis are amenable to treatment with antibiotics, screening for these infections and appropriate treatment would improve outcome of pregnancy.






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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04