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Year : 1999  |  Volume : 17  |  Issue : 3  |  Page : 142-145

Seroprevalence of Chlamydia Trachomatis Antibodies in school going girls VIS-A-VIS Women with bad obstetric history and Secondary infertility


Department of Laboratory Medicine, All Institute of Medical Sciences, New Delhi 110 0029, India

Correspondence Address:
S Singh
Department of Laboratory Medicine, All Institute of Medical Sciences, New Delhi 110 0029
India
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Source of Support: None, Conflict of Interest: None


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ABSTRACT: To provide a base-line data on seroprevalence of Chlamydia trachomatis, serum samples from 114 school going girls (aged 8-15 yrs) were tested for anti-Chlamydia trachomatis IgG and IgA antibodies using commercial enzyme immuno assay kits. The seroprevalence rate in this population was compared with women (n=58) with secondary infertility (group 2) and women with bad obstetric history (BOH) (n=30) (group 3). The results showed that the infection is highly prevalent in young children (28.1 percent) but significantly less than women with secondary infertility in whom it was as high as 48.3 percent (p0.001). Specific IgA antibodies were present in 37.9 percent women as compared to 19.3 percent in girls (p001). Mean OD values of specific IgG and IgA antibodies were also significantly high in women with secondary infertility than women with BOH. Seroprevalence in women with BOH was not significantly higher than girls. Specific IgA antibodies were detected in the vaginal fluids of six married women among 22 serum IgG positive women with BOH was not significantly higher than girls. Specific IgA antibodies were detected in the vaginal fluids of six married women among 22 serum IgG positive women with secondary infertility while only one out of 6 women with BOH was positive for this secretary antibody. This preliminary study indicates that this infection can transmit from person-to-person through non-sexual modes also.






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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

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