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Year : 1999  |  Volume : 17  |  Issue : 3  |  Page : 108-115

Infectious endophthalmitis

Dept. of Microbiology, Vision Research Foundation, Sankara Nethralaya, 18, College Road, Chennai 600 006

Correspondence Address:
HN Madhavan
Dept. of Microbiology, Vision Research Foundation, Sankara Nethralaya, 18, College Road, Chennai 600 006

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Source of Support: None, Conflict of Interest: None

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ABSTRACT: Infectious endophthalmitis is the inflammatory involving the ocular cavity and is commonly caused by bacteria and fungi. It can be classified according to the mode of entry, type of etiological agent and location in the eye. Postoperative endophthalmitis occurs after any surgical procedure resulting in a communication between the interior of the eye and the external environment, the source of infection commonly being the periocular flora of the patient. Gram positive bacteria account for largest number of cases followed by Gram negative bacteria and fungi Staphylococcus epidermidis is the predominant causative agent. A chronic, low grade, delayed-onset post-operative endophthalmitis is typical of Propionibacterium acnes endophthalmitis. Post-traumatic endophthalmitis is mainly caused by Bacillus cereus. Endogenous endophthalmitis is most often fungal with Candida albicans being the most common agent. Etiological diagnosis of suspected endophthalmitis is essential to establish appropriate and timely treatment for a successful visual outcome. Culture of intra-ocular specimens is the gold standard but molecular techniques such as PCR have been found to be more sensitive in detection of the infectious agent. Early identification and antimicrobial susceptibility pattern of the agent can help in prompt treatment of endophthalmitis, which consists of intravitreal antimicrobials and vitrectomy.

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2004 - Indian Journal of Medical Microbiology
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