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Year : 1995  |  Volume : 13  |  Issue : 2  |  Page : 57-64

Animal models in leprosy


Department of Experimental Leprosy and Microbiology, Central JALMA Institute for Leprosy (ICMR) Tejganj, Agra 282 001, India

Correspondence Address:
UD Gupta
Department of Experimental Leprosy and Microbiology, Central JALMA Institute for Leprosy (ICMR) Tejganj, Agra 282 001
India
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Source of Support: None, Conflict of Interest: None


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ABSTRACT: This review shows that much attention has been paid historically to search for animal models for leprosy. After one hundred and twenty years of these investigation, three species of armadillos, normal mice thymectomised irradiated rats/mice, nude mice, SCID mice, Biege mice and four non-human primates (Gibbon, Ape, Rhesus, African green and Mangabey monkeys) have been shown to be useful or potentially useful. Chimpanzees could be added further to the list but more extensive experimental studies are necessary to establish their usefulness.






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2004 - Indian Journal of Medical Microbiology
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