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Year : 1995  |  Volume : 13  |  Issue : 1  |  Page : 37-40

Rapid diagnosis of neonatal bacteraemia

Department of Microbiology, Osmania Medical College, Hyderabad, A.P

Correspondence Address:
M Parikh
Department of Microbiology, Osmania Medical College, Hyderabad, A.P

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Source of Support: None, Conflict of Interest: None

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ABSTRACT: Clinically suspected 254 cases of bacteraemia in neonates admitted to Neonatology unit of Niloufer hospital, Hyderabad. were evaluated by blood culture and rapid diagnostic tests viz., total neutrophil count, immature to total neutrophil (I:T) ration, C-reactive protein assay (CRP), nitroblue tetrazolium test (NBT) and acridine orange stained buffy coat smear (AOS) using fluorescent microscope. Blood culture was positive in 119 (47 percent) of cases. Escherichia coli was the commonest organism isolated in 49 (41.2 percent). The rapid diagnostic tests were evaluated in blood culture positive and blood culture negative cases. it was found that CRP had the highest sensitivity; AOS had the highest specificity and the highest positive predictive accuracy. The sensitivity. specificity and positive predictive accuracy of combination of three tests namely (CRP, NBT and AOS) were better compared to the results of each test.

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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04