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Year : 1995  |  Volume : 13  |  Issue : 1  |  Page : 34-36

Siderophore production by clinical isolates of klebsiella pneumoniae


Department of Microbiology, Panjab University, Chandigarh 160 014, India

Correspondence Address:
B Jaya
Department of Microbiology, Panjab University, Chandigarh 160 014
India
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Source of Support: None, Conflict of Interest: None


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ABSTRACT: Klebsiella pneumoniae is not an intracellular pathogen and hence iron is not readily accessible to this organism in the body. To circumvent their in vivo iron restriction K.pneumoniae produces siderophores i.e. enterochelin and aerobactin, which are capable of removing iron from host iron-binding proteins. In the present study it was observed that almost all the clinical isolates of K.pneumoniae produced enterochelin (98.6 pre cent) whereas the percentage of aerobactin producers was only 65.78. A large number of urinary isolates elaborated aerobactin (82.9 per cent) which shows that there might be a positive correlation between nephropathogenicity and aerobactin production.






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2004 - Indian Journal of Medical Microbiology
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