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Year : 1992  |  Volume : 10  |  Issue : 2  |  Page : 126-132

Experimental Induction Of Cervical Carcinoma By Herpes Simplex Virus Type-2 In Rabbits : Gynaecological, Cytopathological And Immunological Evaluations.



Correspondence Address:
M Elanchezhiyan


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Evaluation of rabbits as experimental animal model for Herpes simplex virus type-2 (HSV-2) (HV-219 Strain) induced cervical carcinoma resulted in the development of a neoplastic condition in the form of leukoplakic patches only. On Papanicolaou’s staining, these areas revealed intra-nuclear vacuolization. The production of leukoplakic changes correlated with increase in the antibody level against HSV-2.






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