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Year : 1990  |  Volume : 8  |  Issue : 2  |  Page : 36-39

Characterization Of Klebocin Plasmids In Klebsiella Pneumoniae



Correspondence Address:
D. R Arora


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Properties of kelbocin plasmids ie stability, curing phage restriction, pilus formation, fertility inhibition and molecular weight was studied in 6 strains of K.pneumoniae. These Plasmids were found to be highly stable in the host strains of K. pneumonia in which they persisted for more than 15 years. However, they were less stable in recipient strain of E. coli. Two of these strains lost these plasmids in 1.5 years while other 4 lost these in 2 years. Caring could not be accomplished with sub-inhibitory concentrations of acriflavine, acridine orange and sodium dodecyl sulphate in any of them. However, one strains could be cured by growing it at 44 + 0.5 C on third subculture. Molecular weight of klebocin plasmids has been found to be 10 X 106.






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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04