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Year : 1990  |  Volume : 8  |  Issue : 1  |  Page : 1-4

Enterotoxigenicity Of Campylobacter Jejuni/Coli In Rat Ileal Loops



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S Anupurba


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Seven human and seven chicken strains of Campylobacter jejuni/coli were tested for enterotoxigenicity in ligated ileal loops of rats. Both live cells and culture filtrates of all the strains caused fluid accumulation in rat loops indicating production of enterotoxin by them. However, 2 human and 5 chicken strains required 1-3 consecutive passage(s) to do so. Ligated rat ileal loop is, therefore, a good experimental model for testing enterotoxigenicity of C.jejuni/coli. The enterotoxic activity of C.jejuni/coli in rat loops was completely neutralized by cholera antitoxin upto 1 in 80 dilution indicating immunobiological similarity between C.jejuni/coli enterotoxin and cholera toxin.






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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04