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Year : 1988  |  Volume : 6  |  Issue : 4  |  Page : 275-282

Comparative Evaluation Of SAFA, PHA and SPRIA In Serodiagnosis Of Pulmonary Tuberculosis Using H37RV Sonicated Antigen



Correspondence Address:
P. K Aggarwal


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Source of Support: None, Conflict of Interest: None


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10 cases of typical mycobacteriosis, 12 cases of atypical mycobacteriosis and 10 healthy control subjects were studied for the presence of antibodies against soni-cate antigen of M. Tuberculosis H37Rv, using soluble antigen fluorescent antibody technique (SAFA), Passive haemagglutination test (PHA) and Solid phase radio-immunoassay technique (SPRIA). The positive reaction with these tests were 80%, 60% and 70% respectively in typical mycobacterial group, while it had been reduced to 41.6%, 8.3% and 8.3% respectively in atypical group. In contrast to this, normal healthy group had 30%, 10% and 20% positive reaction. The sensitivity and specificity of these tests were discussed.






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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04