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Year : 1986  |  Volume : 4  |  Issue : 3  |  Page : 191-197

Effect Of A Fungal Interferon Inducer (6-MFA) On Macrophage Functions During Dengue Virus Infection


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Effect of 6-MFA, an interferon inducer of fungal origin having antiviral activity, was investigated on the functions of macrophages during dengue virus (DV) infection. It was observed that treatment of mice with 6-MFA abrogated the DV induced depression of attachment and phagocytosis of opsonized sheep erythrocytes by the peritoneal macrophages. This effect appears to be mediated by interferon. 6-MFA had no effect on the outcome of infection.






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2004 - Indian Journal of Medical Microbiology
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