Effect Of A Fungal Interferon Inducer (6-MFA) On Macrophage Functions During Dengue Virus Infection

Indian Journal of Medical Microbiology

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Year : 1986 | Volume : 4 | Issue : 3 | Page : 191-197

Effect Of A Fungal Interferon Inducer (6-MFA) On Macrophage Functions During Dengue Virus Infection

Rachna Nagar, U. C Chaturvedi, A Mathur
,

Correspondence Address:
Rachna Nagar

Effect of 6-MFA, an interferon inducer of fungal origin having antiviral activity, was investigated on the functions of macrophages during dengue virus (DV) infection. It was observed that treatment of mice with 6-MFA abrogated the DV induced depression of attachment and phagocytosis of opsonized sheep erythrocytes by the peritoneal macrophages. This effect appears to be mediated by interferon. 6-MFA had no effect on the outcome of infection.

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